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KMID : 1103720220830040958
Journal of the Korean Society of Radiology
2022 Volume.83 No. 4 p.958 ~ p.964
Pulmonary Multinodular Epithelioid Hemangioendothelioma with Mixed Progression and Spontaneous Regression during a 7-Year Follow-Up: A Case Report and Review of Imaging Findings
Lee Ga-Young

Kim Yoo-Kyung
Kim Kwan-Chang
Park Heae-Surng
Abstract
Pulmonary epithelioid hemangioendothelioma (PEH) is a rare vascular tumor of borderline or low-grade malignancy, and its prognosis is unpredictable. Herein, we describe the case of a 47-year-old asymptomatic female with a diagnosis of multinodular PEH. During a 7-year follow-up, the nodules with large size and high 18F-fluorodeoxyglucose uptake in the initial study showed progression with increasing sizes; however, most small nodules (size < 1 cm) demonstrated spontaneous regression with peripheral rim or nodular calcification. The patient underwent surgical resection for an enlarged nodule. Of note, it is unusual for an individual to have mixed progression and regression concomitantly, which may be helpful in predicting the prognosis.
KEYWORD
Hemangioendothelioma, Epithelioid, Computed Tomography, X-Ray, Positron Emission Tomography Computed Tomography
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